Sinocort Tablet Adverse Reactions

Patients receiving corticosteroids should be watched closely for the following adverse reactions which may be associated with any corticosteroid therapy: Fluid and electrolyte disturbances: Sodium retention, fluid retention, congestive heart failure in susceptible patients, potassium loss, hypokalemic alkalosis, and hypertension.
Musculoskeletal: Muscle weakness, fatigue, steroid myopathy, loss of muscle mass, osteoporosis, vertebral compression fractures, aseptic necrosis of femoral and humeral heads, pathologic fractures of long bones, and spontaneous fracture.
Gastrointestinal: Peptic ulcer with possible perforation and hemorrhage, pancreatitis, abdominal distention, and ulcerative esophagitis.
Dermatologic: Impaired wound healing, thin fragile skin, petechiae and ecchymoses, facial erythema, increased sweating, subcutaneous fat atrophy, purpura, striae, hyperpigmentation, hirsutism, acneiform eruptions, and suppressed reactions to skin tests.
Neurological: Convulsions, increased intracranial pressure with papilloedema (pseudotumor cerebri) usually after treatment, vertigo, headache, neuritis or parasthesia and aggravation of preexisting.
Endocrine: Menstrual irregularities; development of the Cushingoid state; suppression of growth in children; secondary adrenocortical and pituitary unresponsiveness particularly in times of stress (e.g. trauma, surgery, or illness); decreased carbohydrate tolerance, manifestations of latent diabetes mellitus; and increased requirements for insulin or oral hypoglycemic agents in diabetes.
Ophthalmic: Posterior subcapsular cataracts, increased intraocular pressure, glaucoma, and exophthalmos.
Metabolic: Hyperglycemia, glycosuria, and negative nitrogen balance due to protein catabolism.
Others: Necrotizing angiitis, thrombophlebitis, thromboembolism aggravation or masking of infections, insomnia, syncopal episodes, and anaphylactoid reactions, Hypersensitivity including anaphylaxis, Leucocytosis and leucopenia, thromboembolism, vertigo, flushing of the face, fatigue and nausea is rare possibility.